e054971.full.pdf

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• The search strategy was designed by combining the terms for bacteria and carbapenem resistance (see online supplemental appendix 1). The search terms for the bacteria were ‘Enterobacteriaceae’, along with ‘Klebsi- ella pneumoniae’ and ‘Escherichia coli’, (the two most clin- ically important pathogens within the Enterobacteriaceae family). The search terms for carbapenem resistance were ‘carbapenem-resistant’, ‘carbapenem resistance’, ‘carbapenem non-susceptible’ and ‘carbapenemase- producing’ because CRE can be generally divided into carbapenemase-producing CRE (CP-CRE) and non-CP- CRE

• Data were extracted from each selected study into a data extraction form in Excel.

• The Enterobacteriaceae species, mainly Kleb- siella pneumoniae and Escherichia coli, can cause infections like bloodstream infections

• ventilator- associated pneumonia, intra- abdominal infections and urinary tract infec- tions in both healthcare and community settings