Eszopiclone: Uses, Interactions, Mechanism of Action | DrugBank Online
go.drugbank.com/drugs/DB00402
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improving both the latency phase and the maintenance phase of sleep.
It is the active stereoisomer of zopiclone,
One major benefit of eszopiclone is that it is approved by the FDA for the long-term treatment of insomnia.
This sets it apart from many other hypnotic sedatives, which are generally approved only for the relief of short-term (6-8 weeks) insomnia.
Eszopiclone rapidly induces sleep and decreases sleep latency. It also aids in the maintenance of sleep, preventing frequent awakenings.
These include changes in alertness and motor coordination and the risk of next morning impairment, increasing with the amount of eszopiclone administered.
Advise patients to skip the eszopiclone dose if alcohol has been consumed before bed or during the evening.
Though the potential for dependence and abuse with eszopiclone is lower than for other hypnotic drugs, this drug has been abused and is known to cause dependence.
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