onlinelibrary.wiley.com/doi/abs/10.1111/bjd.14906
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Oxidative stress is the resultant damage due to redox imbalances (increase in destructive free radicals [reactive oxygen species (ROS)] and reduction in antioxidant protection/pathways) and is linked to ageing in many tissues including skin
fibroblasts which provide a potential ageing biomarker
most widely accepted ageing theories describing subsequent increasing free radical generation
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