Zika virus is a pathogen that poses serious consequences, including congenital microcephaly
whether Zika virus alters cellular metabolism and the functional consequences of Zika-induced metabolic changes remain unknown
Inhibiting AMPK in human cells decreases Zika virus-mediated cell death, whereas activating AMPK in mosquito cells promotes Zika virus-mediated cell death.
the differential metabolic reprogramming during Zika virus infection of human versus mosquito cells determines whether cell death occurs.
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