Differential Metabolic Reprogramming by Zika Virus Promotes Cell Death in Human versus Mosquito Cells
www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30064-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413119300646%3Fshowall%3Dtrue
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Zika virus is a pathogen that poses serious consequences, including congenital microcephaly
whether Zika virus alters cellular metabolism and the functional consequences of Zika-induced metabolic changes remain unknown
Inhibiting AMPK in human cells decreases Zika virus-mediated cell death, whereas activating AMPK in mosquito cells promotes Zika virus-mediated cell death.
the differential metabolic reprogramming during Zika virus infection of human versus mosquito cells determines whether cell death occurs.
arthropod-borne virus
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