“Surprisingly, not very much is known about why or how exercise builds muscles: there’s a lot of anecdotal knowledge and acquired wisdom, but very little in the way of hard or proven data,” said University of Cambridge physicist Eugene Terentjev.
Still, even with centuries of experience and knowledge under our weightlifting belts, there’s two big questions we’ve yet to answer, Terentjev and co-author Neil Ibata wrote: How do the muscles know they’re being exercised? And what signals do they give off to cause their physiological change?
When put under a lot of force, or worked for a prolonged amount of time, the growth signals have more time to bind, so titin can tell your cells to get to work building muscle.
Their model predicted that the best amount of force for building muscle is around 70% of your maximum load
Lift below 70%, and you may not keep that titin window open long enough for optimal muscle building; go higher, and “rapid exhaustion prevents a good outcome, which our model has quantitatively predicted,” Terentjev said.
more research needs to be done
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