Human Papillomavirus E6 and E7: The Cervical Cancer Hallmarks and Targets for Therapy
www.frontiersin.org/articles/10.3389/fmicb.2019.03116/full
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since p53 is degraded by E6 successfully, the angiogenesis inhibitors are not functiona
constitutively to establish replicative immortality. E6 has been reported to activate the hTERT promoter with the help of cellular ubiquitin ligase-E6AP along with c-myc, Sp1, and NFX1
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