Region-specific Dissociation of Neuronal Loss and Neurofibrillary Pathology in a Mouse Model of Tauopathy

www.ncbi.nlm.nih.gov/pmc/articles/PMC1606598/

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Tau

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although neurofibrillary tangles correlate with neuronal loss in AD, the amount of loss far exceeds the amount of tangle formation.8 Thus, whether tangles cause neuronal death remains unclear.

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Simone Attanasio

Are Tau Tangles causative for neuronal loss?

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