Alu elements as regulators of gene expression
www.ncbi.nlm.nih.gov/pmc/articles/PMC1636486/
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were at the origin considered as parasites of the genome that had no major effect on its stability and genic expression. They were thought to be ‘selfish’ or ‘junk’ DNA
Alu elements are the most abundant repetitive elements in the human genome; they emerged 65 million years ago from a 5′ to 3′ fusion of the 7SL RNA gene and amplified throughout the human genome by retrotransposition
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