Protein–small molecule interaction
Discovering new drug molecules and drug targets
Because functional protein microarrays are constructed using individually purified proteins, they enable the study of various biochemical properties of proteins, such as binding activities, including protein‐protein, protein‐DNA, protein‐lipid, protein‐drug, and protein‐peptide interactions, and enzyme‐substrate relationships via various types of biochemical reactions
Moreover, protein microarrays enable the study of many post‐translational modifications (i.e., phosphorylation, acetylation, ubiquitylation, S‐nitrosylation) in a large‐scale fashion, which is critical for understanding cellular protein synthesis and function
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