RB1, ARF, WIF1, PTEN and TSSC3 were shown to trigger autophagy
several oncogenes activated in osteosarcoma such as IGF2, H19, COPS3 and RUNX2 also regulate autophagy
Finally, different studies evidenced that the mTOR pathway was overactivated in osteosarcoma, suggesting autophagy inhibition
Role of autophagy in osteosarcoma
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