different miRNAs expression in HPV-positive tumor cells compared to the negative counterpart
the early (E) region coding proteins regulating viral transcription (E2), viral DNA replication (E1, E2), cell proliferation (E5, E6, E7), and viral particle release (E4), and the late (L) region which encodes the structural proteins (L1 and L2). E5, E6, and E7 are viral oncogenes; several studies on mucosal HR HPVs have established that E6 and E7
Feng et al. reported high levels of PIWIL2 in high-grade cervical intraepithelial neoplasia (CIN) and in CSCC, whereas in healthy tissue and low-grade CIN PIWIL2 was weakly expressed . Additional
gesting GATA6-AS might play a role in CSCC through an HPV-independent pathway . The study of Wang et al., that was already discussed above, reported 19 lncRNAs that were differentially expressed between HPV-p
HPV infection could stimulate estrogen receptor α to increase lnc-IL17RA-11 expression in order to upregulate the activity of genes involved in processes that enhance sensitivity to radiation therapy
chematic diagram of Human Papilloma Virus (HPV) E6/E7 oncoproteins affecting long non-coding RNAs (lncRNAs) expression in cervical squamo
MEG3 methylation had high power to discriminate high-grade CIN patients f
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