The effects of prior exposure to testosterone during puberty on the performance of transgender women (TW) undergoing physical effort are not well known
All TW were non-gonadectomized subjects and were in estrogen plus cyproterone acetate therapy
Mean total testosterone (ng/dL) levels of TW, CW and CM were 83.5, 20.5 and 480.5 at the time of the study, respectively
The mean maximum strength was 31,9 kg (SD±2.4) in TW, 29.2 kg (SD±4.4) in CW, and 47.5 (SD±8.6) in CM
FFM, a mean of 0.54 was observed in the TW group, and 0.76 in the CW and CM
The expression of muscle strength/FFM is the same in CM and CW, which suggests that the innate quality of the muscles as well as their motor control is similar in these groups
After GAHT muscle strength of TW is equal of CW.
There is a decrease in the functionality of the muscular unit in producing strength in this group of TWs
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