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Progenitor-Based Cell Biological Aspects of Neocortex Development and Evolution

www.ncbi.nlm.nih.gov/pmc/articles/PMC9119302/

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  • Development of the neocortex is based on spatio-temporally restricted transcriptional programs that unfold in a sequential manner and are a predominant factor for the neural progenitor cell proliferation, differentiation, migration and specification of different neuronal subtypes in the neocortex

  • Specifically, the various progenitor cells in the developing neocortex reside in two germinal zones—i) the ventricular zone (VZ), the primary germinal zone; and ii) the subventricular zone (SVZ), a secondary germinal zone

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