Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells
www.sciencedirect.com/science/article/abs/pii/S1534580723004033
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metabolic transition
surrounding somatic cells flatten the 16-cell differentiating cyst, resulting in an increase of the membrane tension of germ cells inside the cyst.
maintain cytosolic Ca2+ concentration in germ cells through a mechanically activated channel, transmembrane channel-like
CaMKI-Fray-JNK signaling relay, leading to the transcriptional activation of OXPHOS in differentiating cysts.
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