tumor cell evolution and to predict gene function
Our research also spans cancer evolution, immuno-oncology, translational genomics, biomarker discovery, tumor metabolism and genetic ancestry effects
to develop new technologies and use engineering techniques to solve fundamental problems in biology and to better understand, diagnose, and treat cancer.
believe in the potential of cancer engineering to transform diagnosis and treatment.
nanotechnology, imaging, immuno-engineering, integrative computational biology, and genetic engineering, along with unparalleled access to cutting-edge tools such as nanomaterials, CRISPR, organoids, atomic force microscopes, and 3D printers
a variety of backgrounds, including those with an engineering or physical science focus.
Researchers are developing novel nanomaterial delivery platforms using biomaterial scaffolds, inorganics, and nanocarbons for the targeted delivery of small molecule and biologic therapies, including RNA.
how to target the delivery of nanotherapeutics into cancer
prostate-specific membrane antigen (PSMA) and P-selectin modes of targeting,
We study and leverage nanotechnology and engineer biomaterials to make foundational biological discoveries in living cells and tissues,
advanced imaging and probe development, utilizing components such as small molecules, proteins, and nanoparticles
Our research efforts have led to clinical translation for a number of new cancer imaging probes,
Memorial Sloan Kettering faculty were the first to report the potential of chimeric antigen receptor (CAR) T cells to induce remissions in adult patients with refractory acute lymphoblastic leukemia
the Computational and Systems Biology Program and the Computational Oncology Program
d major discoveries in biology and oncology and developed next generation computational tools and platform
statistical methods to identify cell states
how they change across developmental time or under disease conditions
nd to discover the genes that drive these change
, RNA splicing and regulation, and how certain proteins bind specifically to DNA or RNA.
MSK-SPECTRUM (Spatio-temporal evolution of cancer traced using multimodalities)