AD begins deep in the brain where healthy neurons begin to work less efficiently and eventually die.
memory center—the hippocampu
three distinct stages of the disease:
brain atrophy (shrinkage).
accumulation of beta-amyloid plaques
decreased glucose metabolism
beta-amyloid plaques and neurofibrillary tangles
PET and MR imaging.
PET scans are able to measure the brain’s rate of glucose metabolism using the tracer 18F-Fluorodeoxyglucose (FDG).
the temporal and parietal lobes– show decreased glucose metabolism.
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