Overview of heavy proteinuria and the nephrotic syndrome - UpToDate
www.uptodate.com/contents/glomerular-disease-evaluation-and-differential-diagnosis-in-adults?search=nephrotic%20syndrome&source=search_result&selectedTitle=8~150&usage_type=default&display_rank=8
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Adult-onset primary membranous nephropathy and FSGS may be due to autoantibodies to podocyte antigens or circulating factors that affect the podocyte. The engagement or activation of these podocyte proteins alters the arrangement of the slit diaphragm or podocyte cytoskeleton
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